Abstract: Measurement for satellite’s thermal control voltage is an important part to guarantee satellite’s reliability and security. Because the particularity of the measurement, it needs to research and design a voltage measurement module which is fit for the whole satellite’s thermal control system. Signals isolation and input protection are used to guarantee the safety of measurement, and techniques of advanced data collection, quantity conversion and automatic calibration are used for reliability of measurement. The measurement process is controlled by microprocessor, and the computer’s data transfer and communication control are realized by LAN interface, the efficiency of measurement is improved a lot.