Abstract: A new method for amplitude measurement based on time comb technology is introduced in this paper. The principle of time comb is given, and its characteristic is analyzed .The principle is used in data acquisition of high frequency. Equivalent sampling technology is abstained，avoiding high sampling frequency and combined with autocorrelation and multilayer autocorrelation technology，Then amplitude is detected when the Nyquist sampling theorem is not satisfied. Simulation results shows that the high resolution for high frequency signals especially in low signalnoise ratio condition.

Key words: Time comb technology, Equivalent sampling, Amplitude measurement